Virkon™ DISINFECTANT/CLEANER P.W.S. VIRUCIDE Vetoquinol DIN 02125021 Bactericide, Fungicide DEODORANT DANGER: EYE AND SKIN IRRITANT READ THE LABEL AND LEAFLET BEFORE USING Broad spectrum germicide for cleaning and disinfection of agricultural buildings such as dairy barns, horse barns, piggeries, poultry houses, shelter sheds and other types of livestock buildings. Also for use in veterinary and human hospitals and healthcare facilities, and food processing plants. Virkon™ is a broad-spectrum virucidal hard surface disinfectant that is expected to inactivate SARS-CoV-2 (the virus that causes COVID-19). INDUSTRIAL CAUTION POISON GUARANTEE/ACTIVE INGREDIENT: Potassium monopersulfate 21.4% W/W DESCRIPTION Virkon™ is a disinfectant, possessing wide spectrum virucidal (Table 2), bactericidal (Table 3) and fungicidal (Table 4) activity. The effectiveness of Virkon™ is further enhanced by its excellent detergent properties, so that clean disease-free surfaces can be achieved. Virkon™ is unique in its composition. Its activity is based on a buffered synergized acid peroxygen system containing a high percentage of surfactant. Virkon™ can be used on all surfaces and in all situations. Once diluted in a 1% solution, Virkon™ is of low toxicity, non-tainting, and non-irritant. Because of its high detergency and mode of action, Virkon™ can be used in an exceptional variety of situations for effective cleaning and virucidal disinfection in a single operation. Virkon™ can be applied manually or through all types of cleaning and spraying equipment. Readily soluble in lukewarm water giving a clear pink solution. Virkon™ consists mainly of inorganic salts. DETERGENT SANITIZER Virkon™ passes the AOAC germicidal and detergent sanitizer test at a concentration o 0.5% (1:200). DIRECTIONS FOR USE CAUTION: Persons must leave and animals/poultry must be removed from premises prior to disinfection. Avoid contact with food. Empty all feeding and watering appliances. All surfaces and/or object that will contact food, feed or drinking water should be rinsed thoroughly with potable water before reuse. Following disinfection, ensure areas have been ventilated prior to persons and animals/poultry entry. 1. FOR CLEANING AND DISINFECTION OF SURFACES AND EQUIPMENT: In agricultural buildings Remove all animals from premises. Remove all litter and manure from floors, walls, and other surfaces of barns and equipment. Brush and blow dust from fans, motors, louvers and electrical equipment. For terminal cleaning and disinfection, saturate all surfaces with a 1% w/v solution of Virkon™, using a pressure washer or a fogger. Virkon™ should remain in contact with the surface to be disinfected for at least 10 minutes. Scrub heavily soiled utensils and soak in a 1% w/v solution of Virkon™ for 10 minutes (do not exceed 30 minutes for metal objects). In veterinary and human hospitals and healthcare facilities Remove all animals from the room. Persons must leave the room. Remove heavy soil deposits then thoroughly wet surfaces to be disinfected with a 1% w/v solution of Virkon™, using a mop, sponge or cloth, as well as by spraying. A minimum contact time of 10 minutes is required. For laboratory equipment and bowls, scrub heavily soiled utensils and soak in a 1% w/v solution of Virkon™ for a minimum of 10 minutes (do not exceed 30 minutes for metal objects). IMPORTANT NOTE: In animal premises where there has been a disease outbreak and/or the mortality/morbidity rates are higher than normal and the causative agent has been determined by a pathology laboratory to be one of those listed in Table 1, the contact time/dilution rate indicated should be used. This product is not to be used as a sterilant/high-level disinfectant on any surface or instrument that: (1) is introduced directly into the human body, either into or in contact with the bloodstream or normally sterile areas of the body, or (2) contacts intact mucous membranes but which does not ordinarily penetrate the blood barrier or otherwise enter normally sterile areas of the body. This product may be used to pre-clean or decontaminate critical or semi-critical medical devices prior to sterilization or high-level disinfection. In food processing plants Remove all debris and other deposits from surfaces. Then, thoroughly wet surfaces to be disinfected with a 1% w/v solution of Virkon™, using a mop, sponge or cloth, as well as by spraying. A minimum contact time of 10 minutes is required. For food contact surfaces, rinse thoroughly with potable water after treatment with Virkon™. For a complete listing of microorganisms against which Virkon™ is effective, refer to the Efficacy Charts 2, 3, and 4. 2. FOR AERIAL DISINFECTION: To replace dangerous and ineffective formalin fumigation in empty farm buildings and veterinary hospitals. Shutdown the ventilation system during the disinfection. Use a mechanical fogging machine as part of terminal disinfection routine with a 1% w/v solution of Virkon™. Apply at a rate of one litre of solution per 100 m3 with particle size not exceeding 70 microns in order to get a minimal contact time of 10 minutes with microorganisms in the air. Leave the room during the fogging. Users and animals may re-enter the treated area once the fog has dispersed. No rinsing is required after fogging. 3. SANITIZING DRINKING WATER SYSTEM: For sanitizing drinking water system at terminal clean out, use a 1.0% w/v solution of Virkon™. Dose header tank and drain system. Wait at least 10 minutes before draining again. DILUTION INSTRUCTIONS Quantity of disinfectant solution required Dilution rate required (w/v) 3.0% 2.0% 1.0% 0.5% 0.2% Quantity of Virkon™ required 30 g 20 g 10 g 5 g 2 g 1 Litre 150 g 100 g 50 g 25 g 10 g 5 Litres 300 g 200 g 100 g 50 g 20 g 10 Litres 750 g 500 g 250 g 125 g 50 g 25 Litres 1) Select the quantity of disinfectant solution required. 2) Choose appropriate dilution rate. 3) Measure out the amount of Virkon™ indicated using the graduated measuring scoop provided. 4) Add Virkon™ to warm water and stir. There is a 20% loss of activity of 1% solutions of Virkon™ after 14 days in 350 ppm hard water. HEALTH AND SAFETY: FIRE HAZARD: NON-FLAMMABLE PRECAUTIONS: Keep out of reach of children. Powder irritating to eyes, skin and mucous membranes. May be harmful if swallowed or inhaled. Do not get powder in eyes. Avoid contact of powder with skin. Handle in such a way as to minimize dust release. Do not mix with other chemicals. When mixing the solution, wear goggles, chemical-resistant gloves, and a mask. It is recommended that workers wear overalls, goggles and a mask when applying Virkon™ solution with a hand-held fogger or a pressure washer. DISPOSAL 1) Rinse the emptied container thoroughly and add the rinsings to treatment site. 2) Follow provincial instructions for any required additional cleaning of the container prior to its disposal. 3) Make the empty container unsuitable for further use. 4) Dispose of the container in accordance with provincial requirements. 5) For information on the disposal of unused, unwanted product and the cleanup of spills, contact the Provincial Regulatory Agency or the Manufacturer. FIRST AID Eyes: Irrigate with plenty of water. Skin: When in powder, remove contaminated clothing. Wash with soap and water. Not hazardous when in solution. Ingestion: When in powder, wash mouth with plenty of water. Drink plenty of water. Do not induce vomiting. Seek medical advice. If in solution, rinse mouth out with water. Inhalation: When in powder, if symptoms of coughing, choking, wheezing are troublesome, remove to fresh air and seek medical advice. STORAGE Store between 15°C and 25°C in a dry place in tightly sealed containers. PRESENTATION Pouch of 50 g, Bottle of 500 g, Pail of 5 kg and 10 kg. TABLE 1: Micoorganisms for which a dilution rate of Virkon™ >1% w/v or a contact time >10 minutes are required. Microorganism Effective Dilution of Virkon™ Contact Time Required (minutes) Test Method Aspergillus fumigatus 3% 10 AOAC Fungicidal Test Bovine Papilloma Virus 1% 30 VLA, UK Method Dermatophilus congolensis 2% 10 AOAC Use Dilution Test Fusarium moniloforme 2% 10 AOAC* PRRS Virus 0.5% 30 VLA, UK Method Salmonella enteritidis 2% 10 AOAC Use Dilution Test Trichophyton interdigitale 2% 10 AOAC* * Modification of AOAC Fungicidal Test TABLE 2: Viruses for which a 1% w/v dilution rate of Virkon™ and a contact time of 10 minutes are known to be effective. Viruses Effective Dilution of Virkon™ Contact Time Required (minutes) Test Method Avian Infectious Bronchitis Virus 1% 10 AOAC* Avian Influenza Virus 1% 10 AOAC* Avian Laryngotracheitis Virus 1% 10 AOAC* Bovine Adenovirus Type 4 1% 10 EPA Method Bovine Viral Diarrhea (BVD) Pestivirus 1% 10 EPA Method Calf Rotavirus 1% 10 EPA Method Canine Parvovirus 1% 10 EPA Method Duck Adenovirus 1% 10 EPA Method Equine Arteritis Virus 1% 10 EPA Method Equine Herpes Virus Type 1 1% 10 EPA Method Equine Herpes Virus Type 3 1% 10 EPA Method Equine Influenza Virus Type A 1% 10 EPA Method Feline Calicivirus 1% 10 EPA Method Feline Panleukopenia Virus 1% 10 EPA Method Feline Rhinotracheitis Virus 1% 10 EPA Method Infectious Bovine Rhinotracheitis Virus 1% 10 EPA Method Infectious Bronchitis Virus 1% 10 AOAC* Infectious Bursal Disease (Gumboro) Virus 1% 10 AOAC* Infectious Canine Hepatitis Adenovirus 1% 10 EPA Method Newcastle Disease Virus 1% 10 AOAC* Parainfluenza Virus 1% 10 EPA Method Parvovirus 1% 10 EPA Method Pseudorabies Virus 1% 10 EPA Method Simian Virus 40 (SV40) 1% 10 EPA Method TGE-Coronavirus 1% 10 EPA Method Turkey Herpes Virus 1% 10 EPA Method * Modification of the AOAC Fungicidal Test TABLE 3: Bacteria for which a 1% w/v dilution rate of Virkon™ and a contact time of 10 minutes are known to be effective. Bacteria Effective Dilution of Virkon™ Contact Time Required (minutes) Test Method Actinobacillus pleuropneumoniae 1% 10 AOAC* Bordetella avium (Alcaligenes faecalis) 1% 10 AOAC Use Dilution Test Bordetella bronchiseptica 1% 10 AOAC Use Dilution Test Brucella abortus 1% 10 AOAC Use Dilution Test Helicobacter pylori (Campylobacter pyloridis) 1% 10 AOAC Use Dilution Test Campylobacter jejuni 1% 10 AOAC* Chlamydia psittaci 1% 10 EPA Method Erysipelothrix rhusiopathiae 1% 10 AOAC Use Dilution Test Escherichia coli 1% 10 AOAC Use Dilution Test Haemophilus somnus 1% 10 AOAC Use Dilution Test Klebsiella pneumoniae 1% 10 AOAC Use Dilution Test Listeria monocytogenes 1% 10 AOAC Use Dilution Test Moraxella bovis 1% 10 AOAC Use Dilution Test Mycoplasma gallisepticum 1% 10 AOAC Use Dilution Test Pasteurella haemolytica 1% 10 AOAC Use Dilution Test Pasteurella multocida 1% 10 AOAC Use Dilution Test Pseudomonas aeruginosa 1% 10 AOAC Use Dilution Test Salmonella enterica 1% 10 AOAC Use Dilution Test Salmonella typhimurium 1% 10 AOAC Use Dilution Test Serpulina (Treponema) hyodysenteriae 1% 10 AOAC Use Dilution Test Shigella sonnei 1% 10 AOAC Use Dilution Test Staphylococcus aureus 1% 10 AOAC Use Dilution Test Staphylococcus epidermidis 1% 10 AOAC Use Dilution Test Streptococcus equi 1% 10 AOAC Use Dilution Test Streptococcus suis 1% 10 AOAC Use Dilution Test Haemophilus (Taylorella) equigenitali 1% 10 AOAC Use Dilution Test * Modification of the AOAC Use Dilution Test TABLE 4: Fungi for which a maximum 1% w/v dilution rate of Virkon™ and a contact time of 10 minutes are known to be effective. Fungi Effective Dilution of Virkon™ Contact Time Required (minutes) Test Method Candida albicans 1% 10 AOAC Use Dilution Test Microsporum canis 0.5% 10 MHW Guideline, Japan Trichophyton verrucosum 0.5% 10 MHW Guideline, Japan * Modification of AOAC Fungicidal Test